Invention Application
US20120029046A1 CRYSTALLINE FORM OF SUNITINIB AND PROCESSES FOR ITS PREPARATION
审中-公开
SUNITINIB的结晶形式及其制备方法
- Patent Title: CRYSTALLINE FORM OF SUNITINIB AND PROCESSES FOR ITS PREPARATION
- Patent Title (中): SUNITINIB的结晶形式及其制备方法
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Application No.: US13060331Application Date: 2009-08-24
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Publication No.: US20120029046A1Publication Date: 2012-02-02
- Inventor: Vinayak Gore , Bharati Choudhari , Mahesh Hublikar , Prakash Bansode
- Applicant: Vinayak Gore , Bharati Choudhari , Mahesh Hublikar , Prakash Bansode
- Applicant Address: GB Hertfordshire
- Assignee: Generics (UK) Limited
- Current Assignee: Generics (UK) Limited
- Current Assignee Address: GB Hertfordshire
- Priority: IN1434/KOL/2008 20080825
- International Application: PCT/GB09/51054 WO 20090824
- Main IPC: A61K31/404
- IPC: A61K31/404 ; A61P35/00 ; C07D403/06
Abstract:
The present invention relates to a novel crystalline form of sunitinib free base designated form I and to processes for its preparation. The invention also relates to its use as an API and in the preparation of various forms of sunitinib. Further, the invention relates to pharmaceutical compositions comprising the novel crystalline form and salts, solvates and hydrates prepared according to the invention, and to the uses of said pharmaceutical compositions in the treatment and/or prevention of cancer.
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