发明申请
- 专利标题： CONDENSED PYRROLOPYRIDINE DERIVATIVE
- 专利标题（中）： 浓缩吡咯啉衍生物
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申请号： US13264008申请日： 2010-04-13
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公开(公告)号： US20120034250A1公开(公告)日： 2012-02-09
- 发明人: Shohei Shirakami , Yutaka Nakajima , Jun Maeda , Hiroaki Tominaga , Hiroaki Yamagishi , Takeshi Hondo , Masamichi Inami , Hiroki Morio , Takayuki Inoue , Tsuyoshi Mizutani , Hiroki Ishioka
- 申请人： Shohei Shirakami , Yutaka Nakajima , Jun Maeda , Hiroaki Tominaga , Hiroaki Yamagishi , Takeshi Hondo , Masamichi Inami , Hiroki Morio , Takayuki Inoue , Tsuyoshi Mizutani , Hiroki Ishioka
- 申请人地址： JP Tokyo
- 专利权人： Astellas Pharma Inc.
- 当前专利权人： Astellas Pharma Inc.
- 当前专利权人地址： JP Tokyo
- 优先权： JP2009097974 20090414
- 国际申请： PCT/JP2010/056619 WO 20100413
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; A61K31/55 ; A61P37/06 ; A61K31/541 ; A61K31/5377 ; A61K31/496 ; C07D471/14 ; A61K31/497
摘要：
[Problem]The present invention provides a condensed pyrrolopyridine derivative which is useful as an active ingredient for a pharmaceutical composition, in particular, a pharmaceutical composition for preventing or treating diseases caused by undesirable cytokine signal transduction or diseases caused by abnormal cytokine signal transduction.[Means for Solution]The present inventors have extensively studied a compound having a JAK inhibitory action, and as a result, they have found that a condensed pyrrolopyridine derivative which is the compound of the present invention has an excellent JAK inhibitory action, and is therefore useful as an agent for preventing or treating diseases caused by undesirable cytokine signal transduction or diseases caused by abnormal cytokine signal transduction, thereby completing the present invention.
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