Invention Application
- Patent Title: COMPOSITIONS, METHODS AND USES FOR MODULATION OF BRCA 1
- Patent Title (中): 组合物，调整BRCA的方法和用途1
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Application No.: US12937217Application Date: 2009-04-13
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Publication No.: US20120040896A1Publication Date: 2012-02-16
- Inventor: Jeffrey Thomas Holt , Steve Anderson , Andrew Cook Nelson
- Applicant: Jeffrey Thomas Holt , Steve Anderson , Andrew Cook Nelson
- Applicant Address: US CO Denver
- Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO
- Current Assignee Address: US CO Denver
- International Application: PCT/US09/40391 WO 20090413
- Main IPC: A61K38/17
- IPC: A61K38/17 ; A61K38/30 ; A61P35/00 ; A61K31/404 ; A61K31/663 ; C07K16/18 ; A61K38/28
Abstract:
Embodiments of the present invention generally relate to methods, compositions and uses for diagnosis and treatment of cancer. Certain embodiments report methods and compositions for diagnosing and/or treating a subject having a BRCA1-related cancer or sporadic cancer. Some embodiments disclose treatments that can include, but are not limited to, modulation of BRCA1. In some embodiments, methods for identifying a subject with unstable BRCA1 protein are reported.
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