发明申请
US20120053171A1 Nitrogen-Containing Fused Heterocyclic Compounds and Their use as Beta Amyloid Production Inhibitors
失效
含氮混合杂环化合物及其作为β淀粉样蛋白生产抑制剂的用途
- 专利标题： Nitrogen-Containing Fused Heterocyclic Compounds and Their use as Beta Amyloid Production Inhibitors
- 专利标题（中）： 含氮混合杂环化合物及其作为β淀粉样蛋白生产抑制剂的用途
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申请号： US13138504申请日： 2010-02-24
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公开(公告)号： US20120053171A1公开(公告)日： 2012-03-01
- 发明人: Noritaka Kitazawa , Daisuke Shinmyo , Koichio Ito , Nobuaki Sato , Daiju Hasegawa , Toshiyuki Uemura , Toru Watanabe
- 申请人： Noritaka Kitazawa , Daisuke Shinmyo , Koichio Ito , Nobuaki Sato , Daiju Hasegawa , Toshiyuki Uemura , Toru Watanabe
- 优先权： JP2009-043337 20090226
- 国际申请： PCT/JP2010/053368 WO 20100224
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61K31/4985 ; A61K31/496 ; A61K31/4375 ; C07D487/04 ; A61K31/4439 ; C07D498/04 ; A61P25/28 ; C07D471/04 ; A61P25/00 ; A61K31/5365 ; A61K31/437
摘要：
A compound represented by the formula [I]: or a pharmacologically acceptable salt or ester thereof, wherein Ring A represents a five-membered aromatic heterocyclic group or the like fused with a non-aromatic ring group, which may be substituted, Ring B represents a phenyl group or the like which may be substituted, X1 represents a single bond or the like, R1 and R2 each represent a C1-6 alkyl group or the like, m represents an integer of 0 to 3, and n represents an integer of 0 to 2, is effective as a therapeutic agent for a disease caused by Aβ.
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