发明申请
US20120053348A1 METHOD FOR PRODUCING 2-AZAADAMANTANE COMPOUND FROM BICYCLOCARBAMATE COMPOUND
有权
从双氰胺化合物生产2-氮杂异构体化合物的方法
- 专利标题: METHOD FOR PRODUCING 2-AZAADAMANTANE COMPOUND FROM BICYCLOCARBAMATE COMPOUND
- 专利标题(中): 从双氰胺化合物生产2-氮杂异构体化合物的方法
-
申请号: US13265978申请日: 2010-04-23
-
公开(公告)号: US20120053348A1公开(公告)日: 2012-03-01
- 发明人: Masami Kozawa , Yuki Endo
- 申请人: Masami Kozawa , Yuki Endo
- 申请人地址: JP Tokyo
- 专利权人: Nissan Chemical Industries, Ltd.
- 当前专利权人: Nissan Chemical Industries, Ltd.
- 当前专利权人地址: JP Tokyo
- 优先权: JP2009-105926 20090424
- 国际申请: PCT/JP10/57278 WO 20100423
- 主分类号: C07D451/14
- IPC分类号: C07D451/14
摘要:
To provide a novel method for producing a 2-azaadamantane compound from a bicyclocarbamate compound.In accordance with the following scheme: a bicyclocarbamate compound represented by the formula (1) is reacted with a halogenating agent to produce a 2-azaadamantane carbamate compound represented by the formula (2), and the 2-azaadamantane carbamate compound is subjected to hydrogenolysis to produce a 2-azaadamantane compound represented by the formula (3) (in the formulae, R1 is hydrogen or the like, each of R2 and R3 which are independent of each other, is a hydrogen atom or a C1-6 alkyl group, Ar is an aryl group which may be substituted by Ra, Ra is halogen or the like, X is a halogen atom, and Y is X or a hydrogen atom).
公开/授权文献
信息查询