发明申请
- 专利标题： CARBON NANOHORN MRI CONTRAST AGENTS
- 专利标题（中）： 碳纳米星MRI对比剂
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申请号： US13295621申请日： 2011-11-14
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公开(公告)号： US20120058053A1公开(公告)日： 2012-03-08
- 发明人: Sumio Iijima , Jin Miyawaki , Masako Yudasaka , Eiichi Nakamura , Hiroyuki Isobe , Hideki Yorimitsu , Hideto Imai
- 申请人： Sumio Iijima , Jin Miyawaki , Masako Yudasaka , Eiichi Nakamura , Hiroyuki Isobe , Hideki Yorimitsu , Hideto Imai
- 优先权： JP2004-374878 20041224
- 主分类号： A61B5/055
- IPC分类号： A61B5/055 ; B82Y5/00
摘要：
A contrast agent characterized in that each of carbon nanohorns forming a carbon nanohorn aggregate has an opening at the side wall or tip, wherein a metal M (at least one metal selected from among paramagnetic metals, ferromagnetic metals, and superparamagnetic metals) or a compound of the metal M is incorporated in or dispersed on each of the carbon nanohorns. A contrast agent characterized in that it contains a Gd oxide. There is provided a contrast agent, which can be mass-produced easily, and satisfies the requirement of low toxicity and enables microscopic diagnoses when used for MRI. A contrast agent characterized in that is contains a carbon nanohorn aggregate.
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