发明申请
US20120058194A1 PHARMACEUTICAL FORMULATIONS COMPRISING SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
审中-公开
包含取代苯并咪唑衍生物的药物制剂
- 专利标题： PHARMACEUTICAL FORMULATIONS COMPRISING SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
- 专利标题（中）： 包含取代苯并咪唑衍生物的药物制剂
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申请号： US13217901申请日： 2011-08-25
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公开(公告)号： US20120058194A1公开(公告)日： 2012-03-08
- 发明人: Navin Vaya , Mamta Mishra , Atul Shivaji Shinde , Harshal Prabhakar Bhagwatwar , Debashis Dash , Deepti Jain , Rahul Sudhakar Gawande , Vishal Lad , Sushant Dube , Venkateswarlu Vobalaboina , Srinivas Irukulla , Manikandan Ramalingam
- 申请人： Navin Vaya , Mamta Mishra , Atul Shivaji Shinde , Harshal Prabhakar Bhagwatwar , Debashis Dash , Deepti Jain , Rahul Sudhakar Gawande , Vishal Lad , Sushant Dube , Venkateswarlu Vobalaboina , Srinivas Irukulla , Manikandan Ramalingam
- 优先权： IN2475/CHE/2010 20100827; IN3009/CHE/2010 20101011; IN94/CHE/2011 20110111
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K47/38 ; B05D5/00 ; A61K47/44 ; A61K31/4439 ; A61P1/04 ; A61K47/36 ; A61K47/46
摘要：
Stabilized substituted benzimidazole modified release pharmaceutical formulations with at least two drug-containing fractions, wherein the release from a first fraction precedes the release from a second fraction, pharmaceutical excipients, processes for preparing the stable formulations, packaging therefor, and their use in treatment of erosive esophagitis and heartburn associated with non-erosive gastroesophageal reflux disease.