A dispensing system for administration of medicaments during a medicament dosage regime and comprising: (i) a tray comprising an interconnected array of compartments, each compartment being dimensioned to accommodate therein a plurality of medicaments; and (ii) a closure for the compartments arranged so that the closure and the compartments form a series of sealed containers for holding medicaments; the compartments and the closure therefor being arranged so that each sealed container is frangible from the interconnected array so that a sealed container may be removed from the array.