A method and system for preventing gas pressure in a pressure vessel from dropping below a minimum allowable pressure. Pressure readings from a pressure sensor downstream of a pressure regulator are monitored by a processor as they vary within a steady fluctuation band under normal regulated pressure conditions. When the pressure regulator reaches a fully open position in low vessel pressure conditions, the processor detects a drop in the pressure reading to a value below the recent fluctuation band, and recognizes that the pressure is dropping below the regulation pressure value. The processor can use this information to shut off flow of gas from the vessel, thus preventing the vessel from dropping below its minimum allowable pressure, regardless of the actual magnitude of the pressure reading from the sensor—which can vary through a wide range due to tolerances.