发明申请
- 专利标题： BENZAZEPINE COMPOUNDS AS CGRP RECEPTOR ANTAGONISTS
- 专利标题（中）： 苯并噻唑化合物作为CGRP受体拮抗剂
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申请号： US12520146申请日： 2007-12-14
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公开(公告)号： US20120065190A1公开(公告)日： 2012-03-15
- 发明人: Ian M. Bell , Harold G. Selnick
- 申请人： Ian M. Bell , Harold G. Selnick
- 国际申请： PCT/US07/25690 WO 20071214
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; C07D487/04 ; A61P25/08 ; A61P25/06 ; A61P9/12 ; C07D519/00 ; A61P29/00
摘要：
Compounds of formula I: (wherein variables A1, m, R1, R2, R3, R4 and Z are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.