Invention Application
- Patent Title: Transfer Hydrogenation of Cyclopamine Analogs
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Application No.: US13232898Application Date: 2011-09-14
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Publication No.: US20120065400A1Publication Date: 2012-03-15
- Inventor: Daniel G. Genov , Brian C. Austad , Brian H. White
- Applicant: Daniel G. Genov , Brian C. Austad , Brian H. White
- Applicant Address: US MA Cambridge
- Assignee: INFINITY PHARMACEUTICALS, INC.
- Current Assignee: INFINITY PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Cambridge
- Main IPC: C07D491/048
- IPC: C07D491/048

Abstract:
Provided herein is a process for the transfer-hydrogenation of ketone analogs of members of the jervine type of Veratrum alkaloids, such as cyclopamine. Also provided herein are novel ruthenium transfer-hydrogenation catalysts.
Public/Granted literature
- US09376447B2 Transfer hydrogenation of cyclopamine analogs Public/Granted day:2016-06-28
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