发明申请
- 专利标题： PROCESS FOR PREPARATION OF ELETRIPTAN AND SALT THEREOF
- 专利标题（中）： 制备艾司匹坦及其盐的方法
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申请号： US13183911申请日： 2011-07-15
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公开(公告)号： US20120071669A1公开(公告)日： 2012-03-22
- 发明人: Dhananjay Govind Sathe , Subhash Vishwanath Damle , Subodh Shashikant Patnekar , Prashant Vijay Joshi , Samadhan Daulat Patil
- 申请人： Dhananjay Govind Sathe , Subhash Vishwanath Damle , Subodh Shashikant Patnekar , Prashant Vijay Joshi , Samadhan Daulat Patil
- 申请人地址： IN Mumbai
- 专利权人： USV Limited B.S.D. Mar
- 当前专利权人： USV Limited B.S.D. Mar
- 当前专利权人地址： IN Mumbai
- 优先权： IN2035/MUM/2010 20100715
- 主分类号： C07D403/06
- IPC分类号： C07D403/06
摘要：
The present invention relates to an improved process for the preparation of 3-(N-methyl-2(R)-pyrrolidinyl methyl)-5-[2-(phenyl sulfonyl)ethyl]-1H-indole or pharmaceutically acceptable salts thereof, particularly 3-(N-methyl-2(R)-pyrrolidinyl methyl)-5-[2-(phenyl sulfonyl)ethyl]-1H-indole hydrobromide (Eletriptan hydrobromide). The present invention further relates to novel polymorphs of 3-(N-methyl-2(R)-pyrrolidinyl methyl)-5-[2-(phenyl sulfonyl)ethenyl]-1H-indole hydrobromide and process for preparation thereof.
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