In general, a wavelength division multiplexed (WDM) communication system may use wavelength selective switching to simultaneously pre-filter and combine groups of channel wavelengths with orthogonal polarizations to provide a pre-filtered, pair-wise orthogonal aggregate WDM optical signal. An orthogonally-combining wavelength selective switch (WSS) multiplexer may route channel wavelengths individually from different sets of channels to a common output. The orthogonally-combining WSS multiplexer may also provide substantially orthogonal polarizations for the wavelengths in the different sets of channels. The different sets of channels may include odd channels and even channels.