发明申请
US20120093775A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CIRRHOSIS AND LIVER FIBROSIS
审中-公开
用于治疗血栓形成和肝纤维化的方法和组合物
- 专利标题: METHODS AND COMPOSITIONS FOR THE TREATMENT OF CIRRHOSIS AND LIVER FIBROSIS
- 专利标题(中): 用于治疗血栓形成和肝纤维化的方法和组合物
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申请号: US13260654申请日: 2010-03-26
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公开(公告)号: US20120093775A1公开(公告)日: 2012-04-19
- 发明人: Maria Purificaion Fortes Alonso , Jesús Maria Prieto Valtueña , Luciano Matías Sobrevals , Harald Petry , Eric Jacobus Hubertus Timmermans
- 申请人: Maria Purificaion Fortes Alonso , Jesús Maria Prieto Valtueña , Luciano Matías Sobrevals , Harald Petry , Eric Jacobus Hubertus Timmermans
- 申请人地址: ES Navarra
- 专利权人: PROYECTO DE BIOMEDICINA CIMA, S.L.
- 当前专利权人: PROYECTO DE BIOMEDICINA CIMA, S.L.
- 当前专利权人地址: ES Navarra
- 优先权: ESP200900846 20090327
- 国际申请: PCT/ES10/70184 WO 20100326
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; A61P1/16 ; A61K38/00 ; C12N7/04 ; C12N15/63 ; C12N7/00
摘要:
The invention provides a method for the treatment of cirrhosis and liver fibrosis by the use or viral vectors containing the gene encoding IGF-I. The invention discloses both parvoviral vectors and SV40-based vectors as well uses thereof for the treatment of cirrhosis and gene therapy and methods for the preparation of said viral vectors.
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