Embodiments described herein include a substrate media registration system in a printing system. The registration system can include a deskewing system, a reflexive system, and a controller. The deskewing system is configured to deskew substrate media. The reflexive system is configured to detect the lateral position of the substrate media and at least one of a lead edge and a trail edge of the substrate media being transported in the process direction. The controller is operatively coupled to the reflexive system and is configured to control ejection of ink from a print head system in response to detecting the lateral position of the substrate media and at least one of the lead edge and the trail edge of the substrate media.