Method and arrangement in a user equipment for link adaptation of signals sent from the user equipment to a base station. The base station and the user equipment are comprised within a wireless communication system. The method comprises receiving information from the base station, comprising an indication of resource blocks available for transmission of signals from the user equipment to the base station, obtaining at least one of a user equipment related parameter or a link related parameter, and selecting a subset of the indicated available resource blocks received from the base station, based on at least one of the measured user equipment related parameter or the measured link related parameter, to be used for sending signals to the base station. Also, a method and arrangement in a base station for assisting a user equipment in performing link adaptation of signals is presented.