发明申请
US20120100233A1 COMPOSITIONS FOR TREATMENT AND PREVENTION OF DIABETIC COMPLICATIONS USING OSTEOMELES SCHWERINAE
失效
用OSTEOMEL SCHWERINAE治疗和预防糖尿病并发症的组合物
- 专利标题: COMPOSITIONS FOR TREATMENT AND PREVENTION OF DIABETIC COMPLICATIONS USING OSTEOMELES SCHWERINAE
- 专利标题(中): 用OSTEOMEL SCHWERINAE治疗和预防糖尿病并发症的组合物
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申请号: US13381493申请日: 2009-11-05
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公开(公告)号: US20120100233A1公开(公告)日: 2012-04-26
- 发明人: Jin Sook Kim , Dae Sik Jang , Young Sook Kim , Yun Mi Lee , Joo-Hwan Kim , Eunjin Shon , Junghyun Kim , Chan-Sik Kim , Ohn Soon Kim , Dong Ho Jung , Nan Hee Kim , Nam-Hee Yoo , Jun Lee
- 申请人: Jin Sook Kim , Dae Sik Jang , Young Sook Kim , Yun Mi Lee , Joo-Hwan Kim , Eunjin Shon , Junghyun Kim , Chan-Sik Kim , Ohn Soon Kim , Dong Ho Jung , Nan Hee Kim , Nam-Hee Yoo , Jun Lee
- 申请人地址: KR Daejeon
- 专利权人: KOREA INSTITUTE OF ORIENTAL MEDICINE
- 当前专利权人: KOREA INSTITUTE OF ORIENTAL MEDICINE
- 当前专利权人地址: KR Daejeon
- 国际申请: PCT/KR09/06491 WO 20091105
- 主分类号: A61K36/73
- IPC分类号: A61K36/73 ; A61P43/00 ; A61P35/00 ; A61P3/10
摘要:
The present invention relates to a treatment agent for diabetic complications, and a method for the treatment of diabetic complications using the same. The present invention confirmed that Osteomeles schwerinae extract and its fractions inhibited the generation of AGEs, the index for diabetic complications, inhibited the activation of aldose reductase, had anti-cataract activity, and had anti-oxidative activity. Thus, the present invention relates to a preventive and therapeutic agent for diabetic complications containing the said Osteomeles schwerinae extract and its fraction as an active ingredient.
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