发明申请
US20120101274A1 Process For Preparing [1S-[1-alpha, 2-alpha, 3-beta (1S*,2R*) 5-beta]]-3-[7-[2-(3,4-difluorophenyl)-cyclopropylamino]-5-(propylthio)-3H-1,2,3-triazolo [4,5-d] pyrimidin-3-yl]-5-(2-hydroxyethoxy) cyclopentane-1,2-diol And To Its Intermediates
有权
制备[1S- [1-α，2-α，3-β（1S *，2R *）5-β] -3- [7- [2-（3,4-二氟苯基） - 环丙基氨基] 5-（丙硫基）-3H-1,2,3-三唑并[4,5-d]嘧啶-3-基] -5-（2-羟基乙氧基）环戊烷-1,2-二醇及其中间体
![Process For Preparing [1S-[1-alpha, 2-alpha, 3-beta (1S*,2R*) 5-beta]]-3-[7-[2-(3,4-difluorophenyl)-cyclopropylamino]-5-(propylthio)-3H-1,2,3-triazolo [4,5-d] pyrimidin-3-yl]-5-(2-hydroxyethoxy) cyclopentane-1,2-diol And To Its Intermediates](/docs/US/2012-04-26/US20120101274A1/abs.jpg.600x600.jpg)
- 专利标题： Process For Preparing [1S-[1-alpha, 2-alpha, 3-beta (1S*,2R*) 5-beta]]-3-[7-[2-(3,4-difluorophenyl)-cyclopropylamino]-5-(propylthio)-3H-1,2,3-triazolo [4,5-d] pyrimidin-3-yl]-5-(2-hydroxyethoxy) cyclopentane-1,2-diol And To Its Intermediates
- 专利标题（中）： 制备[1S- [1-α，2-α，3-β（1S *，2R *）5-β] -3- [7- [2-（3,4-二氟苯基） - 环丙基氨基] 5-（丙硫基）-3H-1,2,3-三唑并[4,5-d]嘧啶-3-基] -5-（2-羟基乙氧基）环戊烷-1,2-二醇及其中间体
-
申请号： US13062728申请日： 2009-09-08
-
公开(公告)号： US20120101274A1公开(公告)日： 2012-04-26
- 发明人: Martin Hans Bohlin , Helena Hellström , Peter W. Johansson , Ulf G. Larsson , Mikaela Recknagel , Rhony Aufdenblatten , Andreas Weiss , Ursula Weiss
- 申请人： Martin Hans Bohlin , Helena Hellström , Peter W. Johansson , Ulf G. Larsson , Mikaela Recknagel , Rhony Aufdenblatten , Andreas Weiss , Ursula Weiss
- 申请人地址： SE Sodertalje
- 专利权人： ASTRAZENECA AB
- 当前专利权人： ASTRAZENECA AB
- 当前专利权人地址： SE Sodertalje
- 国际申请： PCT/SE2009/050999 WO 20090908
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07D405/12 ; C07D317/44
![Process For Preparing [1S-[1-alpha, 2-alpha, 3-beta (1S*,2R*) 5-beta]]-3-[7-[2-(3,4-difluorophenyl)-cyclopropylamino]-5-(propylthio)-3H-1,2,3-triazolo [4,5-d] pyrimidin-3-yl]-5-(2-hydroxyethoxy) cyclopentane-1,2-diol And To Its Intermediates](/abs-image/US/2012/04/26/US20120101274A1/abs.jpg.150x150.jpg)
摘要：
The present invention is directed to a process for preparing [1S-[1α,2α,3β(1S*,2R*),5β]]-3-[7-[2-(3,4-difluorophenyl)-cyclopropylamino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol and to intermediates useful in the process.
信息查询
