发明申请
- 专利标题： METHOD FOR IMPROVING BIOAVAILABILITY OF LATANOPROST
- 专利标题（中）： 改善LATANOPROST生物利用度的方法
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申请号： US13381631申请日： 2010-06-23
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公开(公告)号： US20120107376A1公开(公告)日： 2012-05-03
- 发明人: Timo Reunamaki , Paula Tervo , Jukka Lokkila , Pertti Pellinen , Paivi Alajuuma , Olli Oksala
- 申请人： Timo Reunamaki , Paula Tervo , Jukka Lokkila , Pertti Pellinen , Paivi Alajuuma , Olli Oksala
- 专利权人： Santen Pharmaceutical Co. Ltd
- 当前专利权人： Santen Pharmaceutical Co. Ltd
- 优先权： EP09397519.1 20090630
- 国际申请： PCT/JP2010/004179 WO 20100623
- 主分类号： A61K31/216
- IPC分类号： A61K31/216 ; A61P27/06 ; A61K9/00
摘要：
The present invention relates to a method for improving ocular bioavailability of latanoprost by adding an organic amine to an aqueous eye drop composition containing latanoprost. The invention further relates to an aqueous eye drop composition in which a better ocular bioavailability of latanoprost is achieved by adding an organic amine, and to a method for treating occular hypertension and glaucoma by administering said composition to a subject in need of such treatment.
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