发明申请
US20120108492A1 LIGAND-SPECIFIC NON-ANTIBODY COMPOUNDS THAT INHIBIT CR2 ACTIVATION AND METHODS OF USE THEREOF
审中-公开
抑制CR2活化的配体特异性非抗体化合物及其使用方法
- 专利标题: LIGAND-SPECIFIC NON-ANTIBODY COMPOUNDS THAT INHIBIT CR2 ACTIVATION AND METHODS OF USE THEREOF
- 专利标题(中): 抑制CR2活化的配体特异性非抗体化合物及其使用方法
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申请号: US13119706申请日: 2009-09-18
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公开(公告)号: US20120108492A1公开(公告)日: 2012-05-03
- 发明人: V. Michael Holers , Jonathan P. Hannan , James Kovacs
- 申请人: V. Michael Holers , Jonathan P. Hannan , James Kovacs
- 申请人地址: US CO Denver
- 专利权人: The Regents of the University of Colorado
- 当前专利权人: The Regents of the University of Colorado
- 当前专利权人地址: US CO Denver
- 国际申请: PCT/US09/57580 WO 20090918
- 主分类号: A61K38/02
- IPC分类号: A61K38/02 ; C07K7/06 ; A61P31/22 ; C07K2/00
摘要:
The present invention describes a novel non-antibody ligand-specific compound that selectively binds to a complement receptor type 2 (CR2) protein, a ligand thereof, or both, wherein the compound competitively inhibits CR2 ligand's binding to a CR2 protein in a standard assay. The present invention also describes compositions and methods of use thereof.
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