发明申请
- 专利标题: B CELL SURFACE REACTIVE ANTIBODIES
- 专利标题(中): B细胞表面反应抗体
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申请号: US13320630申请日: 2010-05-12
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公开(公告)号: US20120121504A1公开(公告)日: 2012-05-17
- 发明人: Christoph Rader , Sivasubramanian Baskar , Michael R. Bishop , Ivan Samija , Jessica M. Suschak
- 申请人: Christoph Rader , Sivasubramanian Baskar , Michael R. Bishop , Ivan Samija , Jessica M. Suschak
- 申请人地址: US MD Bethesda
- 专利权人: The United States of America, as represented by the Secretary, Dept. of Health and Human Svcs.
- 当前专利权人: The United States of America, as represented by the Secretary, Dept. of Health and Human Svcs.
- 当前专利权人地址: US MD Bethesda
- 国际申请: PCT/US2010/034491 WO 20100512
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; G01N33/566 ; A61K51/10 ; A61K49/00 ; C07K16/30 ; A61P35/02 ; B82Y15/00
摘要:
The invention relates to antibodies that are reactive to the cell surface of CD19+ B cells, including B-cell chronic lymphocytic leukemia (B-CLL) cells, and compositions and methods for using such antibodies, including in the diagnosis and treatment of disorders associated with CD19+ B cells, such as B-CLL.
公开/授权文献
- US08877199B2 B cell surface reactive antibodies 公开/授权日:2014-11-04
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