发明申请
- 专利标题: Engineered listeria and methods of use thereof
- 专利标题(中): 工程李斯特菌及其使用方法
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申请号: US11713765申请日: 2007-03-01
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公开(公告)号: US20120121643A1公开(公告)日: 2012-05-17
- 发明人: Thomas W. Dubensky, JR. , Justin Skoble , Peter M. Lauer , David N. Cook
- 申请人: Thomas W. Dubensky, JR. , Justin Skoble , Peter M. Lauer , David N. Cook
- 主分类号: A61K35/74
- IPC分类号: A61K35/74 ; C12N1/21 ; A61P37/04 ; C12N15/63
摘要:
The invention provides a bacterium containing a polynucleotide comprising a nucleic acid encoding a heterologous antigen, as well as fusion protein partners. Also provided are vectors for mediating site-specific recombination and vectors comprising removable antibiotic resistance genes.
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