发明申请
US20120122855A1 BENZOXAZINES, BENZOTHIAZINES, AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY
失效
苯并噻嗪类，苯并嗪类，以及具有NOS抑制活性的相关化合物
- 专利标题： BENZOXAZINES, BENZOTHIAZINES, AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY
- 专利标题（中）： 苯并噻嗪类，苯并嗪类，以及具有NOS抑制活性的相关化合物
-
申请号： US13360029申请日： 2012-01-27
-
公开(公告)号： US20120122855A1公开(公告)日： 2012-05-17
- 发明人: Jailall RAMNAUTH , Subhash C. Annedi , Sarah Silverman , Peter Dove , Shawn Maddaford , Suman Rakhit
- 申请人： Jailall RAMNAUTH , Subhash C. Annedi , Sarah Silverman , Peter Dove , Shawn Maddaford , Suman Rakhit
- 申请人地址： CA Mississauga
- 专利权人： NeurAxon, Inc.
- 当前专利权人： NeurAxon, Inc.
- 当前专利权人地址： CA Mississauga
- 主分类号： A61K31/5415
- IPC分类号： A61K31/5415 ; C07D413/12 ; C07D417/14 ; C07D417/12 ; A61P25/06 ; A61P29/00 ; A61P25/00 ; A61P25/28 ; A61P9/00 ; A61P1/00 ; C07D413/14 ; A61K31/538
摘要：
The present invention features benzoxazines, benzothiazines, and related compounds that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.