Invention Application
- Patent Title: Organic Compositions to Treat Beta-ENaC-Related Diseases
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Application No.: US13355879Application Date: 2012-01-23
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Publication No.: US20120122960A1Publication Date: 2012-05-17
- Inventor: Antonin DE FOUGEROLLES , John L. DIENER , Emma HICKMAN , Gregory HINKLE , Stuart MILSTEIN , Anne-Marie PULICHINO , Andrew SPRAGUE
- Applicant: Antonin DE FOUGEROLLES , John L. DIENER , Emma HICKMAN , Gregory HINKLE , Stuart MILSTEIN , Anne-Marie PULICHINO , Andrew SPRAGUE
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Main IPC: A61K31/713
- IPC: A61K31/713 ; C07K14/00 ; A61P7/00 ; C07K14/79 ; A61P11/00 ; A61P9/12 ; C07H21/02 ; C07K2/00
Abstract:
The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC.
Public/Granted literature
- US08344129B2 Organic compositions to treat Beta-ENaC-related diseases Public/Granted day:2013-01-01
Information query
