发明申请
- 专利标题： DEFENSIN-ANTIGEN FUSION PROTEINS
- 专利标题（中）： 防御素抗原蛋白
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申请号： US13303081申请日： 2011-11-22
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公开(公告)号： US20120134954A1公开(公告)日： 2012-05-31
- 发明人: Larry W. Kwak , Bira Arya
- 申请人： Larry W. Kwak , Bira Arya
- 专利权人： The Gov. of the U.S.A. as represented by the Secretary of the Dept. of Health & Human Services
- 当前专利权人： The Gov. of the U.S.A. as represented by the Secretary of the Dept. of Health & Human Services
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61P35/00 ; A61K39/39 ; A61K39/395 ; A61K48/00
摘要：
The present invention relates to a vaccine for increasing the immunogenicity of a tumor antigen thus allowing treatment of cancer, as well as a vaccine that increases the immunogenicity of a viral antigen, thus allowing treatment of viral infection, including immunodeficiency virus (HIV) infection. In particular, the present invention provides a fusion protein comprising a defensin fused to either a tumor antigen or viral antigen which is administered as either a protein or nucleic acid vaccine to elicit an immune response effective in treating cancer or effective in treating or preventing viral infection.
公开/授权文献
- US08551936B2 Defensin-antigen fusion proteins 公开/授权日：2013-10-08
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