Embodiments of the present invention include systems and methods for a computer-implemented, in-vehicle application platform (VAP) for conducting vehicle-to-business (V2B) communication. A V2B vehicle application layer resides within the vehicle. The VAP comprises a communication layer facilitating reliable message exchange between this vehicle application layer and V2B business applications. The VAP further comprises a HW abstraction layer encapsulating vehicle-specific interfaces both with regard to the CAN bus and the in-vehicle HMI. According to certain embodiments, these layers of the VAP provide their functionality via open, non-proprietary, and well-defined interfaces, allowing for efficient development of V2B applications and enhancing portability of the latter.