发明申请
- 专利标题: INHIBITORS OF CELLULAR NECROSIS
- 专利标题(中): 细胞坏死因子抑制剂
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申请号: US13401561申请日: 2012-02-21
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公开(公告)号: US20120149702A1公开(公告)日: 2012-06-14
- 发明人: Gregory D. Cuny , Prakash Jagtap , Junying Yuan , Alexei Degterev
- 申请人: Gregory D. Cuny , Prakash Jagtap , Junying Yuan , Alexei Degterev
- 申请人地址: US MA Boston US MA Cambridge
- 专利权人: The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College
- 当前专利权人: The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College
- 当前专利权人地址: US MA Boston US MA Cambridge
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; C07D413/06 ; C07D471/04 ; C07D409/06 ; A61K31/4178 ; A61K31/422 ; A61K31/437 ; A61P9/10 ; A61P31/00 ; A61P29/00 ; A61P25/16 ; A61P25/28 ; C07D413/14 ; A61P43/00 ; C07D403/04
摘要:
The present invention relates to compounds and pharmaceutical preparations and their use in therapy for preventing or treating trauma, ischemia, stroke and degenerative diseases associated with cell death. Methods and compositions of the invention are particularly useful for treating neurological disorders associated with cellular necrosis.
公开/授权文献
- US08741942B2 Inhibitors of cellular necrosis 公开/授权日:2014-06-03