A sequence generation method for allowing a reception end to effectively detect a sequence used for a specific channel of an OFDM communication system, and a signal transmission/reception method using the same are disclosed. During the sequence generation, an index is selected from among the index set having the conjugate symmetry property between indexes, and a specific part corresponding to the frequency “0” is omitted from a transmitted signal. In addition, a reception end can calculate a cross-correlation value between a received (Rx) signal and each sequence using only one cross-correlation calculation based on the conjugate symmetry property.