发明申请
US20120164734A1 NUCLEOTIDES ENCODING STOP CODONS IN MULTIPLE READING FRAMES AND METHODS OF USE
审中-公开
在多个读取框架中编码停止编码的核心和使用方法
- 专利标题: NUCLEOTIDES ENCODING STOP CODONS IN MULTIPLE READING FRAMES AND METHODS OF USE
- 专利标题(中): 在多个读取框架中编码停止编码的核心和使用方法
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申请号: US13413850申请日: 2012-03-07
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公开(公告)号: US20120164734A1公开(公告)日: 2012-06-28
- 发明人: Kimberly F. Glassman , Shane E. Abbitt , Karri Klein
- 申请人: Kimberly F. Glassman , Shane E. Abbitt , Karri Klein
- 申请人地址: US IA Johnston
- 专利权人: PIONEER HI BRED INTERNATIONAL INC
- 当前专利权人: PIONEER HI BRED INTERNATIONAL INC
- 当前专利权人地址: US IA Johnston
- 主分类号: C12N15/82
- IPC分类号: C12N15/82 ; C12N5/10 ; A01H5/10 ; C12N15/63 ; C07H21/04 ; A01H5/00 ; C12N15/85 ; C12N1/21
摘要:
Compositions having polynucleotides encoding multiple translational stop signals in more than one reading frame are provided. The compositions include isolated polynucleotides, expression cassettes, and vectors, as well as host cells, prokaryotic organisms, and eukaryotic organisms comprising the polynucleotide(s). Methods include using the polynucleotides to stop translation of an mRNA into a protein, to produce a transformed cell and/or organism comprising the polynucleotide, and to identify transformed cells or organisms of a specific lineage.