Disclosed are a system and method for managing medication. In detail, a user terminal notifies a user of taking medicine and recognizes whether the medicine has been taken by receiving a medication schedule corresponding to an identification code of prescription from a medication management server or generating the medication schedule for itself to thereby interoperate with a medication support device, or the user terminal recognizes whether the medicine has been taken by using a medicine packet and a medicine content area without depending on the medication support device so that a user may easily take a medicine according to the medication schedule and a medication management service may be provided through the user terminal even when the user goes out or moves.