发明申请
- 专利标题： ANIMAL MODELS AND THERAPEUTIC MOLECULES
- 专利标题（中）： 动物模型和治疗分子
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申请号： US13416684申请日： 2012-03-09
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公开(公告)号： US20120167237A1公开(公告)日： 2012-06-28
- 发明人: Allan Bradley , E-Chiang Lee , Qi Liang , Wei Wang , Anais Legent , Ian Kirby
- 申请人： Allan Bradley , E-Chiang Lee , Qi Liang , Wei Wang , Anais Legent , Ian Kirby
- 申请人地址： GB Cambridge
- 专利权人： Kymab Limited
- 当前专利权人： Kymab Limited
- 当前专利权人地址： GB Cambridge
- 优先权： GB0911846.4 20090708; GB0913102.0 20090728
- 主分类号： A01K67/027
- IPC分类号： A01K67/027 ; C12N5/10 ; C12N15/85 ; C12N15/13 ; C07K16/00
摘要：
The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
公开/授权文献
- US09447177B2 Transgenic mouse homozygous for chimeric IgH locus 公开/授权日：2016-09-20