发明申请
- 专利标题： THERAPEUTIC COMPOSITIONS AND METHODS FOR THE PREVENTION OF AUTOIMMUNE DISEASES
- 专利标题（中）： 治疗组合物和预防自身免疫性疾病的方法
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申请号： US13376122申请日： 2010-06-03
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公开(公告)号： US20120171212A1公开(公告)日： 2012-07-05
- 发明人: George Eisenbarth , Li Zhang , John Kappler , Brian Stadinski
- 申请人： George Eisenbarth , Li Zhang , John Kappler , Brian Stadinski
- 国际申请： PCT/US10/37166 WO 20100603
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P3/10 ; C07K16/18 ; A61K39/385 ; A61P37/04
摘要：
The present invention is directed to therapeutic compositions and methods for the prevention or treatment of autoimmune diseases, comprising molecules that disrupt or prevent the assembly of the trimolecular complex required for the T cell immune response comprising the autoantigen, the MHC class II molecule, and the T cell receptor implicated in the autoimmune disease.
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