发明申请
US20120172381A1 Tricyclic Compounds as Modulators of TNF-alpha Synthesis and as PDE4 Inhibitors
有权
三环化合物作为TNF-α合成的调节剂和PDE4抑制剂
- 专利标题： Tricyclic Compounds as Modulators of TNF-alpha Synthesis and as PDE4 Inhibitors
- 专利标题（中）： 三环化合物作为TNF-α合成的调节剂和PDE4抑制剂
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申请号： US13410628申请日： 2012-03-02
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公开(公告)号： US20120172381A1公开(公告)日： 2012-07-05
- 发明人: Adnan M. M. Mjalli , Bapu Gaddam , Dharma Rao Polisetti , Matthew J. Kostura , Mustafa Guzel
- 申请人： Adnan M. M. Mjalli , Bapu Gaddam , Dharma Rao Polisetti , Matthew J. Kostura , Mustafa Guzel
- 申请人地址： US NC High Point
- 专利权人： HIGH POINT PHARMACEUTICALS, LLC
- 当前专利权人： HIGH POINT PHARMACEUTICALS, LLC
- 当前专利权人地址： US NC High Point
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61P11/06
摘要：
The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-α or by PDE4, including but not limited to rheumatoid arthritis.
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