发明申请
- 专利标题： PYRROLIDINE DERIVATIVES
- 专利标题（中）： 吡咯烷衍生物
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申请号： US13342122申请日： 2012-01-02
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公开(公告)号： US20120178761A1公开(公告)日： 2012-07-12
- 发明人: Henner Knust , Matthias Nettekoven , Hasane Ratni , Walter Vifian
- 申请人： Henner Knust , Matthias Nettekoven , Hasane Ratni , Walter Vifian
- 优先权： EP11150352.0 20110107
- 主分类号： A61K31/454
- IPC分类号： A61K31/454 ; C07D207/14 ; A61P25/18 ; C07D403/06 ; A61K31/501 ; C07D401/06 ; A61K31/40
摘要：
The invention provides compounds of formula wherein R1, R2, R3, R4, R5, and R6 are as defined herein or a pharmaceutically suitable acid addition salt thereof. The present compounds are high potential NK-3 receptor antagonists useful for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
公开/授权文献
- US08618303B2 Pyrrolidine derivatives 公开/授权日：2013-12-31