发明申请
- 专利标题： STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS
- 专利标题（中）： 稳定的免疫调节RNA（SIMRA）化合物
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申请号： US13359714申请日： 2012-01-27
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公开(公告)号： US20120183530A1公开(公告)日： 2012-07-19
- 发明人: Ekambar Kandimalla , Tao Lan , Daqing Wang , Lakshmi Bhagat , Sudhir Agrawal
- 申请人： Ekambar Kandimalla , Tao Lan , Daqing Wang , Lakshmi Bhagat , Sudhir Agrawal
- 专利权人： Idera Pharmaceuticals, Inc.
- 当前专利权人： Idera Pharmaceuticals, Inc.
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P37/02 ; A61K39/00 ; A61K47/00 ; C07H21/02 ; A61K31/7088
摘要：
The invention relates to the therapeutic use of novel stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides novel RNA-based oligoribonucleotides with improved nuclease and RNase stability and that have immune modulatory activity through TLR7 and/or TLR8.
公开/授权文献
- US08362233B2 Stabilized immune modulatory RNA (SIMRA) compounds 公开/授权日：2013-01-29
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