发明申请
- 专利标题： COMBINATORIAL THERAPY
- 专利标题（中）： 组合治疗
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申请号： US13171289申请日： 2011-06-28
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公开(公告)号： US20120195908A1公开(公告)日： 2012-08-02
- 发明人: Anan Chuntharapai , Gregory D. Plowman , Marc Tessier-Lavigne , Yan Wu , Weilan Ye
- 申请人： Anan Chuntharapai , Gregory D. Plowman , Marc Tessier-Lavigne , Yan Wu , Weilan Ye
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P7/00 ; C12N9/96 ; C07K16/28
摘要：
The present invention relates to the use of VEGF antagonists and alpha5beta1 antagonists for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to use of a VEGFR agonists and alpha5beta1 agonists to promote angiogenesis and vascular permeability. The present invention also relates to new anti-alpha5beta1 antibodies, compositions and kits comprising them and methods of making and using them.
公开/授权文献
- US08350010B2 Anti-alpha5/beta1 antibody 公开/授权日：2013-01-08