发明申请
- 专利标题： Novel Quinoline-Hepcidine Antagonists
- 专利标题（中）： 新型喹啉 - 肝嘧啶拮抗剂
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申请号： US13390785申请日： 2010-08-19
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公开(公告)号： US20120196853A1公开(公告)日： 2012-08-02
- 发明人: Franz Dürrenberger , Susanna Burckhardt , Peter O. Geisser , Wilm Buhr , Felix Funk , Vincent A. Corden , Tara Davenport , Stefan Jaeger , Mark Slack , Christopher J. Yarnold , Wei Tsung Yau , Stephen M. Courtney
- 申请人： Franz Dürrenberger , Susanna Burckhardt , Peter O. Geisser , Wilm Buhr , Felix Funk , Vincent A. Corden , Tara Davenport , Stefan Jaeger , Mark Slack , Christopher J. Yarnold , Wei Tsung Yau , Stephen M. Courtney
- 申请人地址： CH St. Gallen
- 专利权人： VIFOR (INTERNATIONAL) AG
- 当前专利权人： VIFOR (INTERNATIONAL) AG
- 当前专利权人地址： CH St. Gallen
- 优先权： EP09168255.9 20090820
- 国际申请： PCT/EP10/62117 WO 20100819
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/496 ; A61P3/00 ; A61P7/06 ; A61P19/02 ; A61P13/12 ; A61P9/00 ; A61P29/00 ; A61P19/04 ; A61P1/00 ; A61K31/4709 ; A61P35/00
摘要：
The present invention relates to novel hepcidin antagonists of the general formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for treatment of disorders in iron metabolism, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and AI: anaemia of inflammation).
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