发明申请
- 专利标题： Anti-RANTES Antibodies and Methods of Use Thereof
- 专利标题（中）： 抗RANTES抗体及其使用方法
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申请号： US13207774申请日： 2011-08-11
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公开(公告)号： US20120201826A1公开(公告)日： 2012-08-09
- 发明人: Nicolas Fischer , Marie Kosco-Vilbois , Francois Mach
- 申请人： Nicolas Fischer , Marie Kosco-Vilbois , Francois Mach
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P29/00 ; A61P37/06 ; C07K16/24 ; A61P9/10
摘要：
The invention relates to fully human monoclonal antibodies, and fragments thereof, that bind to the chemokine Regulated upon Activation, Normal T-cell Expressed, and Secreted (RANTES, CCL5), thereby modulating the interaction between RANTES and one of more of its receptors, such as, e.g., CCR1, CCR3, CCR4 and CCR5, and/or modulating the biological activities of RANTES. The invention also relates to the use of these or any anti-RANTES antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.
公开/授权文献
- US08673299B2 Anti-RANTES antibodies 公开/授权日：2014-03-18