发明申请
US20120202227A1 Babesia microti Genomic Clones Containing Novel Antigens Useful in the Diagnosis of Babesiosis
有权
Babesia microti含有新型抗原的基因组克隆可用于诊断巴西菌病
- 专利标题： Babesia microti Genomic Clones Containing Novel Antigens Useful in the Diagnosis of Babesiosis
- 专利标题（中）： Babesia microti含有新型抗原的基因组克隆可用于诊断巴西菌病
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申请号： US13440106申请日： 2012-04-05
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公开(公告)号： US20120202227A1公开(公告)日： 2012-08-09
- 发明人: John G. Hoey , Hannah Venit , Martin E. Adelson , Eli Mordechai , Fernando Valois-Cruz
- 申请人： John G. Hoey , Hannah Venit , Martin E. Adelson , Eli Mordechai , Fernando Valois-Cruz
- 申请人地址： US NJ Hamilton
- 专利权人： MEDICAL DIAGNOSTIC LABORATORIES, LLC
- 当前专利权人： MEDICAL DIAGNOSTIC LABORATORIES, LLC
- 当前专利权人地址： US NJ Hamilton
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C12P21/02 ; C07K14/44
摘要：
Disclosed are the cloning and expression of novel antigens in Babesia microti. The recombinant polypeptides are highly immunogenic. The polypeptides of the present invention provide the basis of a diagnostic assay that is sensitive, rapid and accurate using patient's sera. Also disclosed is an IgG and IgM ELISA using two novel recombinant antigens in the diagnosis of Babesia infection.