发明申请
- 专利标题: COMBINATION
- 专利标题(中): 组合
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申请号: US13500698申请日: 2010-10-08
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公开(公告)号: US20120202835A1公开(公告)日: 2012-08-09
- 发明人: Melissa Dumble , Tona Gilmer , Rakesh Kumar , Peter F. Lebowitz , Shannon Renae Morris , Sylvie Laquerre
- 申请人: Melissa Dumble , Tona Gilmer , Rakesh Kumar , Peter F. Lebowitz , Shannon Renae Morris , Sylvie Laquerre
- 申请人地址: US PA Philadelphia
- 专利权人: GlaxoSmithKline LLC
- 当前专利权人: GlaxoSmithKline LLC
- 当前专利权人地址: US PA Philadelphia
- 国际申请: PCT/US10/51909 WO 20101008
- 主分类号: A61K31/506
- IPC分类号: A61K31/506 ; A61P35/00
摘要:
The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering N-{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide or a pharmaceutically acceptable salt thereof, and N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide, or a pharmaceutically acceptable salt thereof, to a human in need thereof.
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