发明申请
US20120208850A1 METHODS, COMPOUNDS, AND COMPOSITIONS FOR DELIVERING 1,3-PROPANEDISULFONIC ACID
有权
用于递送1,3-丙二酸的方法，化合物和组合物
- 专利标题： METHODS, COMPOUNDS, AND COMPOSITIONS FOR DELIVERING 1,3-PROPANEDISULFONIC ACID
- 专利标题（中）： 用于递送1,3-丙二酸的方法，化合物和组合物
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申请号： US13389606申请日： 2010-08-06
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公开(公告)号： US20120208850A1公开(公告)日： 2012-08-16
- 发明人: Xianqi Kong , Nigel Levens , Abderrahim Bouzide , Stephane Ciblat , Richard Frenette , Johanne Renaud
- 申请人： Xianqi Kong , Nigel Levens , Abderrahim Bouzide , Stephane Ciblat , Richard Frenette , Johanne Renaud
- 申请人地址： CA QC Laval
- 专利权人： BELLUS HEALTH INC.
- 当前专利权人： BELLUS HEALTH INC.
- 当前专利权人地址： CA QC Laval
- 国际申请： PCT/CA2010/001229 WO 20100806
- 主分类号： A61K31/255
- IPC分类号： A61K31/255 ; C07C309/69 ; A61K31/27 ; A61K31/265 ; C07D327/00 ; A61K31/385 ; C07D311/00 ; A61K31/366 ; C07D401/12 ; A61K31/444 ; A61P13/12 ; A61P3/06 ; A61P3/00 ; A61P3/10 ; A61P5/50 ; A61P1/18 ; C07C309/65
摘要：
The invention relates to methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid (1,3PDS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 1,3PDS, either in vitro or in vivo. The invention also relates to sulfonate ester prodrugs of 1,3PDS as well as Gemini dimmers and oligomers of 1,3PDS for the prevention or treatment of associated diseases and conditions.
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