发明申请
- 专利标题: L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF
- 专利标题(中): L-乙酸乙酯及其制备方法
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申请号: US13436642申请日: 2012-03-30
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公开(公告)号: US20120208885A1公开(公告)日: 2012-08-16
- 发明人: Keith Anderson , Jim Behling , Christine Henderson Dougan , Stephen William Watt , Peter Manini , Attilia Figini
- 申请人: Keith Anderson , Jim Behling , Christine Henderson Dougan , Stephen William Watt , Peter Manini , Attilia Figini
- 申请人地址: US CA San Diego
- 专利权人: OCERA THERAPEUTICS, INC.
- 当前专利权人: OCERA THERAPEUTICS, INC.
- 当前专利权人地址: US CA San Diego
- 主分类号: A61K31/195
- IPC分类号: A61K31/195 ; A61P1/02 ; A61P1/16 ; C07C229/26
摘要:
Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.
公开/授权文献
- US08492439B2 L-ornithine phenyl acetate and methods of making thereof 公开/授权日:2013-07-23