Aspects of the invention relate to techniques for diagnosing compound hold-time faults. A profiling-based scan chain diagnosis may be performed on a faulty scan chain to determine observed scan cell failing probability information and one or more faulty segments based on scan pattern test information. Calculated scan cell failing probability information may then be derived. Based on the calculated scan cell failing probability information and the observed scan cell failing probability information, one or more validated faulty segments are verified to have one or more compound hold-time faults. Finally, one or more clock defect suspects may be identified based on information of the one or more validated faulty segments.