Embodiments of the present invention address deficiencies of the art in respect to connectivity management in a heterogeneous network and provide a method, system and computer program product for resilient and reliable end-to-end connectivity in a heterogeneous network. In one embodiment of the invention, a method for resilient and reliable end-to-end connectivity in a heterogeneous network environment can be provided. The method can include creating an instance of an abstracted network resource model (NRM) for a heterogeneous network environment of different network resource nodes. The method further can include binding an application endpoint in the instance of the abstracted NRM with a connectivity endpoint for a first of the different network resource nodes. Finally, the method can include re-binding the application endpoint to a second of the different network resource nodes in response to detecting the outage.