Invention Application
US20120214792A1 THIENO- ADN FURO-PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
审中-公开
组胺H4受体的THIENO-ADN FURO-PYRIMIDINE调节剂
- Patent Title: THIENO- ADN FURO-PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
- Patent Title (中): 组胺H4受体的THIENO-ADN FURO-PYRIMIDINE调节剂
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Application No.: US13456180Application Date: 2012-04-25
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Publication No.: US20120214792A1Publication Date: 2012-08-23
- Inventor: James P. Edwards , Danielle K. Neff , Deborah M. Smith , Jennifer D. Venable
- Applicant: James P. Edwards , Danielle K. Neff , Deborah M. Smith , Jennifer D. Venable
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D491/048 ; C07D243/08 ; A61K31/551 ; A61P37/08 ; A61P11/06 ; A61P27/02 ; A61P11/00 ; A61P9/10 ; A61P19/02 ; A61P1/00 ; A61P1/04 ; A61P17/06 ; A61P17/00 ; A61P37/06 ; A61P7/06 ; C07D495/04
Abstract:
Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
Public/Granted literature
- US08927555B2 Thieno- and furo-pyrimidine modulators of the histamine H4 receptor Public/Granted day:2015-01-06
Information query
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