发明申请
US20120214792A1 THIENO- ADN FURO-PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
审中-公开
组胺H4受体的THIENO-ADN FURO-PYRIMIDINE调节剂
- 专利标题： THIENO- ADN FURO-PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
- 专利标题（中）： 组胺H4受体的THIENO-ADN FURO-PYRIMIDINE调节剂
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申请号： US13456180申请日： 2012-04-25
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公开(公告)号： US20120214792A1公开(公告)日： 2012-08-23
- 发明人: James P. Edwards , Danielle K. Neff , Deborah M. Smith , Jennifer D. Venable
- 申请人： James P. Edwards , Danielle K. Neff , Deborah M. Smith , Jennifer D. Venable
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D491/048 ; C07D243/08 ; A61K31/551 ; A61P37/08 ; A61P11/06 ; A61P27/02 ; A61P11/00 ; A61P9/10 ; A61P19/02 ; A61P1/00 ; A61P1/04 ; A61P17/06 ; A61P17/00 ; A61P37/06 ; A61P7/06 ; C07D495/04
摘要：
Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.