发明申请
- 专利标题: NOVEL 3-HYDROXY-5-ARYLISOXAZOLE DERIVATIVE
- 专利标题(中): 新型3-羟基-5-亚氨基噻唑衍生物
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申请号: US13504749申请日: 2010-10-29
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公开(公告)号: US20120220772A1公开(公告)日: 2012-08-30
- 发明人: Akihiro Okano , Munetaka Ohkouchi
- 申请人: Akihiro Okano , Munetaka Ohkouchi
- 优先权: JP2009-251493 20091030; JP2009-281014 20091210
- 国际申请: PCT/JP2010/069380 WO 20101029
- 主分类号: C07D261/12
- IPC分类号: C07D261/12 ; C07D413/12
摘要:
[Problem]To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases.[Means of solving the problem]A compound of Formula (I): (where p is 0 to 4; j is 0 to 3; k is 0 to 2; a ring A is a specific cyclic group; a ring B is a benzene ring, a pyridine ring, or a pyrimidine ring; X is —CH2—, O, —S(O)i— (i is 0 to 2), or —NR7—; R1 to R6 are specific groups), a salt of the compound, or a solvate of the salt or the compound.
公开/授权文献
- US08455500B2 3-hydroxy-5-arylisoxazole derivative 公开/授权日:2013-06-04
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