A system and method for identifying a deviation during clinical pathway execution. The system comprises: a clinical pathway storage component configured to store a clinical pathway; a semantic relationship storage component configured to store a semantic relationship between activities; a receiver component configured to receive an activity inputted from a user; and an activity matching component configured to judge, based on the semantic relationship between activities, whether the inputted activity matches the requisite activity defined in the clinical pathway, and if it is determined that the inputted activity does not match the requisite activity defined in the clinical pathway, generate a first clinical pathway execution deviation report, wherein the first clinical pathway execution deviation report indicates that an undefined redundant activity is executed. This permits the precision of identifying deviation during clinical pathway execution to be improved.