发明申请
US20120226445A1 Method for Improving a Chromatographic Detection Limit for an Analyte 有权
改进分析物色谱检测限的方法

  • 专利标题: Method for Improving a Chromatographic Detection Limit for an Analyte
  • 专利标题(中): 改进分析物色谱检测限的方法
  • 申请号: US13390885
    申请日: 2010-08-06
  • 公开(公告)号: US20120226445A1
    公开(公告)日: 2012-09-06
  • 发明人: Udo Gellert
  • 申请人: Udo Gellert
  • 申请人地址: DE Muenchen
  • 专利权人: Siemens Atktiengesellschaft
  • 当前专利权人: Siemens Atktiengesellschaft
  • 当前专利权人地址: DE Muenchen
  • 优先权: DE102009038112.0 20090819
  • 国际申请: PCT/EP2010/061510 WO 20100806
  • 主分类号: G06F19/00
  • IPC分类号: G06F19/00
Method for Improving a Chromatographic Detection Limit for an Analyte
摘要:
A method for improving the chromatographic detection limit for an analyte including a) producing a chromatogram with a peak of the analyte, b) calculating a regression straight line for a baseline from measured values of a section without a peak in the chromatogram, c) calculating a regression function from measured values of the peak of the analyte, d) subtracting the regression function from the chromatogram, e) calculating a regression polynomial for the baseline from the values of the chromatogram which have been changed in step d), calculating a further regression function from the measured values of the peak in the produced chromatogram, g) calculating a peak area between the regression polynomial and the further regression function, h) repetition of step d) with the further regression function instead of the regression function and of steps e), f) and g), until the calculated peak area changes by less than a predetermined amount.
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