发明申请
- 专利标题： Pharmaceutical Formulation For Producing Rapidly Disintegrating Tablets
- 专利标题（中）： 用于生产快速崩解片的药物制剂
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申请号： US13416558申请日： 2012-03-09
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公开(公告)号： US20120231042A1公开(公告)日： 2012-09-13
- 发明人: Karl Kolter , Silke Gebert , Sandra Kruse , Michael Schönherr
- 申请人： Karl Kolter , Silke Gebert , Sandra Kruse , Michael Schönherr
- 申请人地址： DE Ludwigshafen
- 专利权人： BASF SE
- 当前专利权人： BASF SE
- 当前专利权人地址： DE Ludwigshafen
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K47/30
摘要：
Provided are pharmaceutical formulations in the form of granules comprising a) about 60-96% by weight of non-film-forming sugars or sugar alcohols, b) about 1-10% by weight of film-forming sugars or sugar alcohols, c) about 3-25% by weight of disintegrants, d) about 0-10% by weight of water-insoluble, film-forming polymers e) about 0-15% by weight of further pharmaceutically customary auxiliaries where the sum of components a) to e) is 100% by weight. Also provided are methods of making and using the pharmaceutical formulations described herein.
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