发明申请
- 专利标题: INHIBITORS OF THE HEDGEHOG PATHWAY
- 专利标题(中): HEDGEHOG PATHWAY的抑制剂
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申请号: US13487559申请日: 2012-06-04
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公开(公告)号: US20120238570A1公开(公告)日: 2012-09-20
- 发明人: Suleyman Bahceci , William Bajjalieh , Jeff Chen , Sergey Epshteyn , Timothy Patrick Forsyth , Tai Phat Huynh , Byung Gyu Kim , James W. Leahy , Matthew Sangyup Lee , Gary L. Lewis , Morrison B. Mac , Grace Mann , Charles K. Marlowe , Brian Hugh Ridgway , Joan C. Sangalang , Xian Shi , Craig Stacy Takeuchi , Yong Wang
- 申请人: Suleyman Bahceci , William Bajjalieh , Jeff Chen , Sergey Epshteyn , Timothy Patrick Forsyth , Tai Phat Huynh , Byung Gyu Kim , James W. Leahy , Matthew Sangyup Lee , Gary L. Lewis , Morrison B. Mac , Grace Mann , Charles K. Marlowe , Brian Hugh Ridgway , Joan C. Sangalang , Xian Shi , Craig Stacy Takeuchi , Yong Wang
- 申请人地址: US CA San Francisco
- 专利权人: EXELIXIS PATENT COMPANY LLC
- 当前专利权人: EXELIXIS PATENT COMPANY LLC
- 当前专利权人地址: US CA San Francisco
- 主分类号: A61K31/517
- IPC分类号: A61K31/517 ; A61K31/519 ; C07D413/04 ; A61P35/00 ; C07D239/84 ; C07D471/04 ; C07D403/12 ; A61K31/5377 ; C07D239/70
摘要:
The present invention is directed to a compound of Formula I or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of Formula I to treat cancer.
公开/授权文献
- US08796294B2 Inhibitors of the hedgehog pathway 公开/授权日:2014-08-05
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